DNASTAR Lasergene Suite


DNASTAR Lasergene is the complete software solution you need for designing primers, cloning genes, multiple sequence alignments, next-gen sequencing and more. DNASTAR Lasergene includes three comprehensive packages that can also be purchased individually: 

Lasergene Molecular Biology
Lasergene Protein
Lasergene Genomics
To get all three packages, purchase DNASTAR Lasergene and have all of your analysis applications in one software solution.

DNASTAR Lasergene includes Lasergene Molecular Biology, Lasergene Protein, and Lasergene Genomics. One bioinformatics software solution to cover traditional sequence analysis, cloning and primer design as well as next-gen sequencing, gene expression, RNA-Seq, ChIP-Seq, and transcriptome analysis.

NGS Specs. 
  1. Reference guided alignment for any size project  
  2. Cancer genomics
  3. Copy number variation (CNV) calculation
  4. Sanger validation of NGS assemblies and variant calls 
  5. Variant detection accuracy >99% 
  6. SNP to structure workflow for modeling impact of mutations on protein structure
  7. De novo genome assembly and contig editing
  8. Editing and gap closure for reference-guided alignments
  9. De novo transcriptome assembly with automRNA annotation • 
  10. RNA-Seq gene expression analysis and statistics, including DESeq2 and EdgeR ChIP-Seq peak detection
  11. Microarray analysis
  12. miRNA discovery and quantification
  13. Combined analysis and visualization of gene expression data from multiple technologies
  14. Alignment of metagenomic sequencing data to biome genomes and gene databases 
  15. De novo assembly of novel sequences
Mol Bio Specs.
  1. Many popular multiple and pairwise sequence alignment methods, including MUSCLE, MAFFT, Clustal Omega, Clustal W, and ParaSail
  2. Whole-genome alignment using MAUVE
  3. Customizable phylogenetic trees
  4. Support for all major cloning methods, including Gibson Assembly, InFusion, Gateway, Multisite Pro Gateway, TOPO, TA Cloning and restriction enzyme techniques
  5. Design and customize primers and probes
  6. Create and share primer catalogs
  7. Assemble reads de novo or against one or more reference sequences 
  8. Assess read alignment, coverage, and SNPs 
  9. Design sequencing primers to improve coverage.
  10. Accurate and fast sequence auto-annotation 
  11. Sequence editing, including automated and batch editing 
  12. Agarose gel simulations 
  13. Gene discovery 
  14. Integrated BLAST searching 
  15. Publication quality graphics
Protein Specs.
  1. Utilize integrated views and analysis methods for sequence, secondary structure, and tertiary structure 
  2. Predict secondary structure characteristics
  3. Predict B-cell epitopes • 
  4. Create molecular and solvent accessible surfaces to visualize predicted epitopes Align entire structures or selected regions 
  5. Create publication-quality graphics 
  6. Visualize conformational changes of nearly 400 animated macromolecular structures
  7. Predict 3D structure for any protein sequence
  8. Model antibody structures and identify antibody/antigen binding sites
  9. Predict protein function, ligand binding sites, and enzyme activity
  10. Model docking for any receptor and ligand pair
  11. Predict binding interactions and energy
  12. Create and model variants on protein structures 
  13. Perform hot-spot scans and improve the fold stability with protein design tools
  14. Based on the top-rated algorithm: I-TASSER 
  15. Large molecule support, up to 2000 residues 
  16. Predict protein structure, function, ligand binding, and enzyme activity 
  17. Advanced user restraint controls & custom templates
  18. Based on SwarmDock, a high-resolution docking algorithm 
  19. Model protein docking and binding interactions
  20. Explore protein flexibility during docking
  21. Model Fv, Fab, VH, sdAb in minutes 
  22. Search a library of antibody frameworks, or provide custom templates 
  23. Ab initio loop modeling for H3 - up to 15 residues
  24. Automated annotation of CDR loops
  25. Create, model, and analyze variants on structure
  26. Calculate energy changes of mutations
  27. Perform serine and alanine variant scans 


  • Multiple Sequence Alignment
  • Sanger Sequence Assembly
  • Virtual Cloning and Primer Design
  • Comprehensive Sequence Analysis
  • Resequencing and Genotyping
  • Transcriptome Analysis
  • Genome Assembly and Editing
  • Metagenomics
  • Supports all major NGS Workflows and technologies
  • Protein Sequence Analysis
  • Protein Modeling 
  • Protein Structure Analysis
  • Protein Structure with Novafold
  • Protein Protein Docking with NovaDock
  • Antibody Modelling with Novafold Antibody
  • Protein Design with Novadesign
License TypesStandalone or Network
Licensing OptionsAnnual or Perpetual
Minimum System Requirement (Mac)64-bit Windows 7, 8.1, and 10; 4 GB RAM*; 400 MB of available hard-disk space; Internet access
Minimum System Requirement (WIN)Mac 10.13 or above; 4 GB RAM*; 520 MB; Internet access
Operating SystemWindows or Mac
Price OptionsAcademic or Commercial
User optionsSingle, Multiple or Site

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