DNASTAR Lasergene Suite
DNASTAR Lasergene is the complete software solution you need for designing primers, cloning genes, multiple sequence alignments, next-gen sequencing and more. DNASTAR Lasergene includes three comprehensive packages that can also be purchased individually:
Lasergene Molecular Biology
Lasergene Protein
Lasergene Genomics
To get all three packages, purchase DNASTAR Lasergene and have all of your analysis applications in one software solution.
DNASTAR Lasergene includes Lasergene Molecular Biology, Lasergene Protein, and Lasergene Genomics. One bioinformatics software solution to cover traditional sequence analysis, cloning and primer design as well as next-gen sequencing, gene expression, RNA-Seq, ChIP-Seq, and transcriptome analysis.
NGS Specs.
- Reference guided alignment for any size project
- Cancer genomics
- Copy number variation (CNV) calculation
- Sanger validation of NGS assemblies and variant calls
- Variant detection accuracy >99%
- SNP to structure workflow for modeling impact of mutations on protein structure
- De novo genome assembly and contig editing
- Editing and gap closure for reference-guided alignments
- De novo transcriptome assembly with automRNA annotation •
- RNA-Seq gene expression analysis and statistics, including DESeq2 and EdgeR ChIP-Seq peak detection
- Microarray analysis
- miRNA discovery and quantification
- Combined analysis and visualization of gene expression data from multiple technologies
- Alignment of metagenomic sequencing data to biome genomes and gene databases
- De novo assembly of novel sequences
Mol Bio Specs.
- Many popular multiple and pairwise sequence alignment methods, including MUSCLE, MAFFT, Clustal Omega, Clustal W, and ParaSail
- Whole-genome alignment using MAUVE
- Customizable phylogenetic trees
- Support for all major cloning methods, including Gibson Assembly, InFusion, Gateway, Multisite Pro Gateway, TOPO, TA Cloning and restriction enzyme techniques
- Design and customize primers and probes
- Create and share primer catalogs
- Assemble reads de novo or against one or more reference sequences
- Assess read alignment, coverage, and SNPs
- Design sequencing primers to improve coverage.
- Accurate and fast sequence auto-annotation
- Sequence editing, including automated and batch editing
- Agarose gel simulations
- Gene discovery
- Integrated BLAST searching
- Publication quality graphics
Protein Specs.
- Utilize integrated views and analysis methods for sequence, secondary structure, and tertiary structure
- Predict secondary structure characteristics
- Predict B-cell epitopes •
- Create molecular and solvent accessible surfaces to visualize predicted epitopes Align entire structures or selected regions
- Create publication-quality graphics
- Visualize conformational changes of nearly 400 animated macromolecular structures
- Predict 3D structure for any protein sequence
- Model antibody structures and identify antibody/antigen binding sites
- Predict protein function, ligand binding sites, and enzyme activity
- Model docking for any receptor and ligand pair
- Predict binding interactions and energy
- Create and model variants on protein structures
- Perform hot-spot scans and improve the fold stability with protein design tools
- Based on the top-rated algorithm: I-TASSER
- Large molecule support, up to 2000 residues
- Predict protein structure, function, ligand binding, and enzyme activity
- Advanced user restraint controls & custom templates
- Based on SwarmDock, a high-resolution docking algorithm
- Model protein docking and binding interactions
- Explore protein flexibility during docking
- Model Fv, Fab, VH, sdAb in minutes
- Search a library of antibody frameworks, or provide custom templates
- Ab initio loop modeling for H3 - up to 15 residues
- Automated annotation of CDR loops
- Create, model, and analyze variants on structure
- Calculate energy changes of mutations
- Perform serine and alanine variant scans
- Multiple Sequence Alignment
- Sanger Sequence Assembly
- Virtual Cloning and Primer Design
- Comprehensive Sequence Analysis
- Resequencing and Genotyping
- Transcriptome Analysis
- Genome Assembly and Editing
- Metagenomics
- Supports all major NGS Workflows and technologies
- Protein Sequence Analysis
- Protein Modeling
- Protein Structure Analysis
- Protein Structure with Novafold
- Protein Protein Docking with NovaDock
- Antibody Modelling with Novafold Antibody
- Protein Design with Novadesign
License Types | Standalone or Network |
Licensing Options | Annual or Perpetual |
Minimum System Requirement (Mac) | 64-bit Windows 7, 8.1, and 10; 4 GB RAM*; 400 MB of available hard-disk space; Internet access |
Minimum System Requirement (WIN) | Mac 10.13 or above; 4 GB RAM*; 520 MB; Internet access |
Operating System | Windows or Mac |
Price Options | Academic or Commercial |
User options | Single, Multiple or Site |
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